Imines, dioxirane oxidation

Imine peroxide, analytical aspects, 744 Imines, dioxirane oxidation, 1153 Immohihzed enzymes, biosensors, 687-8 Immunoassays... 

Efficient oxidation of imines into nitrones can be achieved by using methyl (trilluoromethyl)dioxirane as an oxidant. This method provides enantiopure nitrones derived from 2H -pyrrole 1-oxide (23, 24). 

The cycloaddition of an oxygen atom to the CN double bond, analogous to the epox-idation of CC double bonds, is rare. For example, when the imine 17 is oxidized with in-situ-generated dioxirane (equation 15), the oxaziridine 18 is obtained as the major... 

The formal addition of an oxygen atom across the carbonyl group gives rise to dioxiranes (equation 33). In practice, this reaction is effected with Oxone, and dimethyldioxirane (30) and other dioxiranes have been generated in solutions of their parent ketones. Dioxirane (30) has been implicated in oxidations of alkenes, sulfides and imines. The formal addition of nitrogen across a carbon-oxygen double bond to afford oxaziridines has been reviewed (equation 34). - There are also many methods available for the indirect conversion of carbonyl compounds to aziridines > and thiiranes using multi-step conversions. 

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