Imidazolone propionase

Catabolism The biological degradation of His proceeds through urocanic acid [histidine ammonia lyase (EC 4.3.1.3)] and 4-imidazolone-5-propanoic acid [urocanic acid hydratase (EC 4.2.1.49)]. The imidazo-ione ring is cleaved by imidazolone propionase (EC 3.S.2.7) and furnishes N-formiminoglutaminic acid. Finally, Glu is formed by glutamate formiminotrans-ferase (EC 2.1.2.5) with the cofactor tetrahydrofolic acid. 

Histidine ammonia-lyase 2 urocanate hydratase 3 imidazolone propionase 4 glutamate form-iminotransferase (the enzyme occurs in vertebrates and forms 5-formimino tetrahydrofolic acid)... 

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See also in sourсe #XX -- [ ]

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