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Imatinib nilotinib kinase activation

Chronic myelogenous leukemia Translocation BCR-ABL BCR-ABL (tyrosine-kinase activity) Imatinib, Dasatinib, Nilotinib, Bosutinib... [Pg.51]

Several inhibitors of their tyrosine kinase activity (non-selective from one receptor to the other) are approved for cancer therapy (imatinib, erlotinib, sorafenib and smitinib) and many others are clinically studied (dasatinib, nilotinib, pazopanib, vatalanib, vandetanib...). [Pg.96]

See other pages where Imatinib nilotinib kinase activation is mentioned: [Pg.349] [Pg.237] [Pg.364] [Pg.364] [Pg.209] [Pg.136] [Pg.35] [Pg.13] [Pg.1262] [Pg.54] [Pg.201] [Pg.112] [Pg.1262] [Pg.610] [Pg.82] [Pg.117] [Pg.131] [Pg.136] [Pg.295] [Pg.136] [Pg.137] [Pg.610] [Pg.452]

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Kinase activated

Kinase activity

Kinase imatinib