Imaging methodology

Ability to use quantitative analysis with both imaging methodologies. 

As mentioned previously, the targeted delivery of suitable contrast agents for ultrasound or MRl imaging methodologies would be desirable for many applications. It remains to be seen whether microbubbles, magnetic nanoparticles or other active compounds can cross barriers in vivo (e.g., the endothehum) and can be delivered in sufficient amounts at sites of dis-... 

As noted above, there are three main imaging methodologies ... 

Within the context of MALDl imaging methodology, the term biomarker will be considered to have a very broad meaning. Notably, it will represent a molecular signal in a given sample that, either alone or in combination (or correlation) with a pattern of other molecular signals, can indicate a particular biochemical or biological situation, independent of any question of biomedical statistical validity and/ or reliability for an entire population of individuals. 

Geets X, Lee JA, Bol A, Lonneux M, Gregoire V (2007) A gradient-based method for segmenting FDG-PET images methodology and validation. Eur J Nucl Med Mol Imaging 34 1427-1438... 

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