Ibotenic acid reactions

A similar reaction was used for the synthesis of muscazone from ibotenic acid (Eq 17).40 Only the 2 and 3 positions interchange. 

Most toxic amino acids of fungi are stable substances that do not undergo reactions leading to reduction of their toxicity. Decomposition of the original amino acid, in some cases, yields degradation products that are also toxic, such as the decarboxylation product of ibotenic acid referred to as muscimol (Figure 10.21). 

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