Hyrtios altum

Kobayashi, M. Aoki, S. Gato, K. Matsunami, K. Kurosu, M. Kitagawa, I. (1994) Trisindoline, a new antibiotic indole trimer, produced by a bacterium of Vibrio sp. separated from the marine sponge Hyrtios altum. Chem. Pharm. Bull., 42, 2449-51. 

Kobayashi, M., Aoki, S., Sakai, H., Kawazoe, K., Kihara, N., Sasaki, T., and Kitagawa, I. (1993). Altohyrtin A, a potent anti-tumor macrolide from the Okinawan marine sponge Hyrtios altum. Tetrahedron Lett. 34, 2795-2798. 

Vibrio sp. Sponge (Hyrtios altum) Tris-indolic derivatives — Kobayashi eto/., 1994... 

Four highly cytotoxic 40-member macrolides, altohyr-tins A-C and 5-desacetylaltohyrtin A, were isolated in 1993 from the species Hyrtios altum harvested in Okinawa. These highly cytotoxic molecules are extremely close to spongistatins and cinachyrolides, whose structures have already been presented (see above). A detailed analysis of their stereostructures showed that altohyrtin A is... 

Kobayashi, M Aoki, S Sakai. H Kihara. N Sasaki. T, and Kitagawa, I. (1993g) Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin a, from the Okinawan marine sponge Hyrtios altum. Chem. Pharm. Bull., 41,989-991. 

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