Hyperuricemia uricosuric effect

Small doses (600 mg) of aspirin cause hyperuricemia, but large doses (> 5 g) have a uricosuric effect. Aspirin inhibits uric acid resorption by the tubules in the kidneys. 

Studies with halofenate continue to establish the uricosuric effect of this hypolipidemic agent.5 56 xhe earlier pattern of plasma triglyceride lowering with limited effects on plasma cholesterol levels continues to be observed and the drug appears to be of value in treating patients with hypertriglyceridemia and hyperuricemia. 

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