Hypersensitization optimum

Symptomatic patients may benefit from the instillation of 0.1% to 0.125% pilocarpine into the affected eye three or four times daily. Because of individual variability, various low concentrations of pilocarpine should be attempted to determine the optimum concentration of miotic that alleviates symptoms as periocular discomfort, headache, photophobia, or blurred vision. If a miotic is used in this fashion, the patient should be carefully monitored in anticipation of modifying the drug regimen if the degree of cholinergic hypersensitivity changes over time. 

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