Hyperprolactinemia etiology

Mah PM, Webster J. Hyperprolactinemia etiology, diagnosis and management. Semin Reprod Med 2002 20 365-373. 

Hyperprolactinemia commonly affects women of reproductive age more than men. Although this disorder occurs in less than 1% of the general population, the estimated prevalence in women with reproductive disorders (e.g., amenorrhea) is as high as 9% to 17%.43 Numerous etiologies of hyperprolactinemia are presented in Table 43-5.43,44 Any medications that block... 

Less common etiologies include central nervous system lesions that physically compress the pituitary stalk and interrupt tonic hypothalamic dopamine secretion, resulting in hyperprolactinemia. Increased thyroid-releasing hormone (TRH) concentrations in hypothyroidism can stimulate prolactin secretion and cause hyperprolactinemia. During conditions of renal or liver compromise, the... 

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