Hypericin synthesis

Isolation of hypericin, first named hypericum red , dates back to the beginning of 1800 however, its correct structure and total synthesis was accomplished about one century later [10,31-33], Hypericin, with inorganic... 

Little is known about the biosynthetic origin of hypericin(s) they are related to the anthranoid metabolism and emodin anthrone is possibly their precursor. Synthesis in vitro of hypericin following alkaline dimerization of emodin and oxidation of its reduction derivative, emodine anthrone, has in fact been demonstrated [35,36]. 

Mario Waser was bom in Steyr, Austria in 1977. After studying chemistry at the Johannes Kepler University (JKU) Linz, Austria, he finished his Ph.D. thesis in 2005 in the group of Prof. Dr. Heinz Falk, working on the synthesis of second-generation hypericin-based photosensitizers. After a postdoctoral stay in the group of Prof. Dr. Alois Furstner at the Max-Planck Institut fiir Kohlenforschung (MiiUieim,... 

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