Hypercycle theory

A hypercycle is a more complex organisation form. Its precondition is the presence of several RNA quasi-species which are able to amalgamate chemically with certain proteins (enzymes or their precursors). If such a protein is linked to a quasi-species, the resulting duo favours the replication of a second quasispecies. According to Dyson, the linked populations get stuck in a stable equilibrium. Problems occur at this level Any theory on the origin of replication has the central problem that the replication process must occur perfectly in order to ensure survival . If there are replication errors, these will increase from generation to generation, until the system collapses the error catastrophe has then occurred ... 

BIFURCATION THEORY PRION PLAQUE FORMATION Autocatalytic processes during evolution, HYPERCYCLE AUTOINHIBITION ACTIVATION... 

From the methodological point of view the hypercycle model is the most impressive example of the possibility of unifying detailed biochemical examinations and mathematical models of chemical reactions. Both the prebiotic relevance of the model and its mathematical structure were studied, sometimes critically (e.g. King, 1981 Miiller-Herold, 1983 Szathmary, 1984). It was suggested that the hypercyclic evolution is not as effective as conventional autocatalysis, and the model should be defined by multiple time singular perturbation theory. 

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