Hyperbilirubinemia, menadione toxicity

Menadione and its water-soluble derivatives are potentially toxic in excess and have been reported to cause hemolytic anemia, hyperbilirubinemia, central nervous system toxicity, and methemoglobinemia in the newborn. 

The toxicity associated with excessive amounts of vitamin K in humans has not been unequivocally defined, although it has been suggested that excessive doses of one of its forms, menadione, can contribute to the occurrence of hemolytic anemia, jaundice, kemicterus, and hyperbilirubinemia (Worthington-Roberts, 1988). 

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See also in sourсe #XX -- [ ]

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