2-Hydroxypyrimidine, complexes with water

The examples discussed above refer to adduct ion formation, where covalent bonds are formed in the Cl plasma. However, with the increasing importance of alternative ionization techniques, such as thermospray (TSI) and, in particular, electrospray ionization (ESI), a wealth of non-covalent ion/molecule adduct ions can be generated and studied nowadays. One recent example concerns the formation of ion/solvent adducts, [M- -So]+, with M including 3-aminophenol, 3-(methylamino)phenol and 3-(dimethylamino)phenol, and several hydroxypyrimidines, among other aromatic molecules. The relative abundances of ions [M- -H]+, [M -h So -h H]+ and [M - - 2 So - - H]+ were studied as a function of the temperature and the pH, with the solvents being mixtures of methanol/water and acetonitrile/water which may contain ammonium acetate as an additive . Quite in contrast to this empirical study on proton-bound ion/molecule complexes, the non-covalent, open-shell adduct ions [l + -h NH3] were investigated with respect to their intrinsic reactivity. These adduct ions were generated from phenol and ammonia by laser ionization of a... 

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