Hydroxyl act

RGURE 8-8 Hydrolysis of RNA under alkaline conditions The 2 hydroxyl acts as a nucleophile in an intramolecular displacement. The 2, 3 -cyclic monophosphate derivative is further hydrolyzed to a mixture of 2 - and 3 -monophosphates DNA, which lacks 2 hydroxyls, is stable under similar conditions... 

Anomeric phosphorylation by glycosylation methods In the above-discussed phosphorylation methods, the sugar hydroxyl acts as the nucleophile and the phosphorylating agent as the electrophile. However, phosphorylation of the anomeric centre may also be performed by another approach where the saccharide contains a leaving group. 

C-2 hydroxyl acts as a H-bond acceptor, with restricted space in the receptor binding cavity around this position. ... 

The pairs, once separated, can induce chemical redox transformations with the species adsorbed on the surface, subject to thermodynamic constraints. It is generaUy assumed that surface hydroxyls act as hole traps by producing OH radicals ... 

The band at 3715 cm is attributed to hydroxyls acting as H-donors, while the band at 3510 cm to hydroxyls acting as H-acceptors. Some authors support assignment of the 3510 cm band to Si—OH pairs (646), whereas others have broadened the assignment to include H-bonded hydroxyl chains (614). 

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