10-hydroxy-l 0-methyl

Hydroxy-2-methyl-l-athyl- 658 1 -Hydroxy-2-methyl-1-butyl- 658... 

Anhydrous HF added to 4-keto-4-methyl-7-(l-naphthyl)heptanoic acid chilled in an ice-salt mixture, and, after 5 min., the reagent evaporated in a current of air — / -(1-hydroxy-2-methyl-l,2,3,4-tetrahydro-l-phenanthryl) propionic acid lactone. Y 93%.—HF proved to be better than H,S04. (W, S. Johnson, Y. L. Stromberg, and J. W. Petersen, Am. Soc. 71,1384 (1949).)... 

Plumbagin (5-hydroxy-2-methyl-l,4-naphthaquinone) [481-42-5] M 188.1, m 78-79", pKEst(i) 9.5, pKEst(2) ll 0. Crystd from aqueous EtOH and sublimed in a vac. Steam distils. 

Tributyl[( )-l-(methoxymethoxy)-2-butenyl]stannane reacts with aldehydes on heating to give (Z)-anti-1 -hydroxy-2-methyl-3,4-enol ethers103. 

H ydroxy-2 -met hyl -4,5 -dicar boxy-15 7 f 1 -Hydroxy-4-methyl-l,4-dihydro- 373 3-Hydroxy-2 -methyl -4,5 -dimethoxycarbonyl - / 5<9... 

Ceftriaxone Ceftriaxone, 7-[[(2-amino-4-lhiazolyl)-2-(Z)-(methyoximino)acetyl]amino]-8-oxo-3-[[(l,2,5,6-tetrahydro-2-methyl-5,6-dioxo-l,2,4-triazin-3-yl)thio]methyl]-5-thia-l-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid (32.1.2.72), is synthesized by acylating 7-amino-3-[[(2,5-dihydro-6-hydroxy-2-methyl-l,2,4-triazin-5-on-3-yl)thio]methyl]3-cefem-... 

Dichloro-l. 2.2-trifluoro-ethyl)-heptafluoro- E10b2. 144 (Eduet) 4.6-Diethy -l-hydroxy-2-methyl-l-(4-trifluoro-plienyl)- E17f., 637 (Cyclis. Benzophenone-Der.) 4.6 Diisopropyl-2.2-dimethyM-hydroxy-l-(4-trifluoromcthyl-phenyl)- E17f. 637 (Cyclis. Benzophenon-Dcr.)... 

Benzo d]-l,2,3-diazaborin 1 -Hydroxy- 2-methyl-1,2-dihydro-XIII/3b, 188... 

Cyclopentan 2-(2-Cyan-ethyl)-3-hydroxy-2-methyl-l-oxo- E21d. 4172 (Oxo H/OH) Cyclopenta b pyrrol 2-Ethoxycarbo-nyl-l,4.5,6-tetrahydro- E6a, 607 [2-Nj - 3-(2-COOR -ethyli-den) — 1 -cyclohexen A] Essigsaure... 

Dihydro-2-hydroxy-2-methyl-l(2//)-naphthalenone (7), a model for many natural products, is obtained in >95% ee via oxidation of the sodium enolate of 3,4-dihydro-2-methyl-1 (2f/)-naphthalenone (5) with ( + )-[(8,8-dichlorocamphoi)sulfonyl]oxaziridine (6)88. This material was obtained in less than 16% ee using (j-)-(camphorsulfonyl)oxaziridine 26. 

Benzyloxy-methyl)-1 -(1 -hydroxy-2-butenyl)-l-trimethylsilyl- 1495 l-(a-Hydroxy-4-methoxy-benzyl)-2-(2-methyl-l -propenyl)-] -Irimelhylsilyl- 1371, 1495... 

Hexyl-1 -hydroxy-2-methyl-seleno-octvl)-l -methylseleno-1499... 

Hydroxy-2-oxo-l-methyl- 802 4-Ilydroxy-3-oxo-2.2,4-trimethyl-l-vinyl- 804 M ethoxy- 660... 

Hydroxy Alkyl Phenyl Ketones The basic structures, 2-hydroxy-2-methyl-l-phenyl-1-propanone HAP and 1-hydroxy-cyclohexyl-1-phenyl ketone HCAP, are also well known [17] and still largely used (10.10) and studied [2i,f,18]. The para substitution of the benzoyl group (with an amino, an ether, or a thioether group) drastically changes the electronic transitions but does not significantly affect the reactivity of the derived benzoyl initiating radical. 

Vitamin K,. 4-Amino-2-methy -l -naphthalenoi 4-amina-2-methyl-i -naphtha 1 -hydroxy-2-methyl-4-ami-nonaphthalene. 2 -meth yl >4-amino-1 -hydroxynaphthalene 2-methyl-4-amino -1 -tiaphthol 3-methyl-4-hydroxy -I ... 

S)-4-Cyclohexyl-1-[[(R)-((S)-1-hydroxy-2-methyl-propoxy](4-phenylbutyl)phosphinyllacetyl-L-proline propionate (ester). 

The first compound, 2-hydroxy-2-methyl-l-pyridin-3-yl-propan-l-one was previously found to be water soluble and very reactive. The activity of this compound was found to be comparable to its phenyl analog, 2-hydroxy-2-methyl-1 phenyl-propane-1-one. All compounds showed absorption maxima about 410 to 430 nm. 

Hydroxy-2-methyl-l-phenylpropane-l-one gives a reaction similar to that of Equation (1.80) and produces radicals by UV irradiation ... 

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