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Hydrophobic interaction oligonucleotides

Aptamers are short DNA or RNA oligonucleotides, specifically selected from oligonucleotide library for binding of a selected protein. The sequence of the aptamer determines its secondary structure, which is responsible for highly specific binding with the selected protein due to hydrophobic interactions and hydrogen bonding. [Pg.336]

The retention of oligonucleotides on reversed phase stationary phases is dominated by the hydrophobic interactions between the nucleotide bases and the stationary phase. Since these interactions are relatively... [Pg.167]


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Hydrophobic interactions

Hydrophobic/hydrophobicity interactions

Hydrophobized interaction

Oligonucleotide hydrophobic interaction

Oligonucleotide hydrophobic interaction

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