Hydrophobic aglycone

Interactions between GAG chains and various molecules or pathogens play many important biological functions. p-o-Xylopyranosides with a hydrophobic aglycon can penetrate the plasma membrane, initiate the first galactosylation step, and act as an exogenous primer for GAG biosynthesis. Hence, these xylosides have demonstrated interesting biological properties such as anti-thrombotic activity, preservation of human skin properties, and antiproliferative activity. Due to major... 

Specificity studies of the rat liver ClGalT have shown that the enzyme is specific for GalNAc acceptor substrates and acts on GalNAc linked to peptide or hydrophobic aglycone groups. The enzyme requires the... 

Table 6 Influence of the size of the hydrophobic aglycon of the fructofuranosidic additive on the selectivity of the aqueous aldolisation,...

Saponins are a diverse group of surface-active heteroglycosides occurring mainly in plants. Hydrophobic aglycones of saponins, which are called sapogenols (formerly sapogenins) are compounds... 

Methods of synthesis of glycosides. - The 2-(dimethyloctylsilyl)ethyl group can be used at a hydrophobic aglycon which allows the use of reversed phase adsorbants for easy product isolation following enzymic glycosylation. ... 

FIGURE 4 Structure of a typical Gypsophila saponin. Note that amphiphilic structure includes a hydrophobic aglycone (30C) and two hydrophilic sugar chains attached at carbon positions 3 and 28 of the aglycone. The most crucial difference between Gypsophila saponins and other saponins is the formyl group at the position C-4. 

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