Hydrogenation of Nitrogen-Containing Multiple Bonds and Reductive Amination

HYDROGENATION OF NITROGEN-CONTAINING MULTIPLE BONDS AND REDUCTIVE AMINATION 

Catalytic hydrogenation of nitriles may result in several products primary, secondary, and tertiary amines imines hydrocarbons aldehydes amides and 

R =H aldirrine cat = Pt, Pd, Rh, R-Ni RT=R ketimine acidic, basic, or neutral media 

Hydrogenations of aromatic nitro compounds are important in industry. A nitro group can be easily introduced into a benzene ring and then hydrogenated to the amine. During the hydrogenation, a number of coupling and alkylation reactions are possible as depicted in Fig. 2.31. 

FIGURE 2.31 Reactions associated with hydrogenation of nitro groups. 

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Hydrogenation of Nitrogen-Containing Multiple Bonds and Reductive Amination... 

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