Hydrogen complex formation with basic

The relatively high basicity of Dz was confirmed by studies of its behavior as the proton acceptor in hydrogen bond formation with phenol in CCI4. For example, the shifts of absorption maxima, Av, from free to complexed Dz and D4 under these conditions are 211 and 159 cm , respectively. 

In the dihydrochloride (602), the second molecule of acid is not firmly bound because of protonation of the second basic site by internal hydrogen bond formation. This would suggest that in the dipicrate, one mole of picric acid participates in salt formation, and that the second mole of picric acid is added to the hydrogen-bonded cation (LXI) forming a molecular complex. The existence of a monopicrate might thus serve to point out structures with steric inhibition of hydrogen bonding. 

Since the stationary phase is basically nonpolar in RPC, it is not expected to effect solute retention by ionic attraction, hydrogen bonding, formation of charge transfer complexes, or by any of the other strong non-covalent interactions familiar to the chemist. The only attractive force between the stationary phase and the eluite would seem to be van der Waals forces. However, these farces also act between the eluite and the mobile phase so that the net effect is generally not sufficien to account for the strong retention often observed with nonpolar compotinds in RPC. 

The hydrogen ion in protophobic aprotic solvents is very reactive. For example, judging from the values of transfer activity coefficient, H+ in AN is 10s times more reactive than in water. Thus, if basic substances are added to the solution in AN, they easily combine with H+. Table 3.6 shows the complex formation con-... 

If the diagram is analyzed in the context of the principles of conjugated reaction, it may be concluded that conjugated biooxidation with hydrogen peroxide consists of the basic (primary) catalase reaction of H202 dissociation (reaction (6.17)). Owing to the Chance complex formation [116, 117], this primary reaction induces the secondary non-classical peroxidase reaction (6.18). 

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