Hydrogen Bonding-Mediated Self-assembly of Aromatic Supramolecular Duplexes

Hydrogen Bonding-Mediated Self-assembly of Aromatic Supramolecular Duplexes 

Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou 310018, China 

Beijing National Laboratory for Molecular Sciences, CAS Key Laboratray of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Seienees, Beijing 100190, China e-mail cchen iccas.ac.cn 

Recently, there is great interest in the artificial construction of molecular duplexes to mimic the structure and function of the above-mentioned double helical structure of DNA and P-sheet structure of protein. Amide-derived peptidomimetics are the most widely used modules for this purpose, inspired by the chemical structures of peptides and also by the mature synthetic methods [3]. Aliphatic peptidomimetics are prone to form helical structures. Because of their relatively rigid stmctures, aromatic peptidomimetics are the most widely used modules in the field. 

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