Hydrogen-bonded molecular aggregates solubility

All known life forms on Earth are surrounded by bilayer membranes that exploit the unique behavior of molecular structures that have, in one part, hydrophobic units built primarily from nonpolar carbon-carbon and carbon-hydrogen bonds and, in another part, polar bonds involving heteroatoms. The first part of the molecule is insoluble in water and therefore aggregates. The second part is soluble in water and presents itself to bulk water solvent, sequestering the hydrophobic parts of the molecule to the interior. 

At the molecular level, various specific and non-specific solvent-solute interactions may occur in polysaccharide solutions that may result in a change in the conformational shape, solubility, viscosity and other hydrodynamic and thermodynamic properties. Hydrophilic interactions such as hydrogen bonding and electrostatic interactions are believed to be factors that influence the conformation of polysaccharides in solution, although the question is being raised (more and more) as to the implication of patches of hydrophobic intermolecular interactions, especially for chain aggregations. One important feature is the... 

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