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Hydrogen-bonded DNA base pairs

Aida, M., Characteristics of the Watson-Crick type hydrogen-bonded DNA base pairs An ab initio molecular orbital study, J. Comput. Chem. 9, 362-368 (1988). [Pg.136]

Sponer, J., Leszczynski, J., and Hobza, P, Structures and energies of hydrogen-bonded DNA base pairs. A nonempirical study with inclusion of electron correlation, J. Phys. Chem. 100, 1965-1974(1996). [Pg.136]

The double-helical strand of a DNA molecule. The diagram at the left shows the hydrogen bonding between base pairs adenine-thymine and cystosine-guanine that hold the strands together. [Pg.629]

The DNA structure involves two polyanionic phosphodiester strands linked together by hydrogen bonding of base pairs. The strands can be separated by a denaturation process (melting). The melting temperatnre increases with an increase in guanine (G)-cytosine (C) content, since this base pair possess three hydrogen bonds as compared to just two for the adenine (A)-thymine (T) pair. [Pg.432]

Hybridization occurs when two complemented strands of DNA or RNA come together as n result of the hydrogen bonding between base pairs. [Pg.448]

Hydrogen bonding between base pairs of the DNA doubie heiix... [Pg.174]

Figure 19-17 also indicates that flat, aromatic molecules can be inserted between the flat, hydrogen-bonded nucleotide base pairs of DNA. We say that the flat molecule is intercalated between the base pairs. One of many analytical applications of aptamers utilizes a molecular light switch intercalated in the aptamer. [Pg.413]

In Figure 16.15 we show a schematic representation of the duplex formed from d(GAATTC). Bases from one monomer pair with those from a second to form the duplex. G forms base-pairs with C, and A with T through hydrogen bonding. These base-pairs are referred to as Watson-Crick base-pairs, and they make up the rungs of the ladder associated with the familiar double helix of DNA. [Pg.248]

The structures of RNA molecules consist of a single polymer chain of nucleotides with the same bases as DNA, with the exception of thymine, which is replaced by uracil, which forms a complementary base pair with adenine (Figure 1.33(a)). These chains often form single stranded hairpin loops separated by short sections of a distorted double helix formed by hydrogen bonded complementary base pairs (Figure 1.33(b)). [Pg.31]

Tautomerization plays a vital role in biological systems as well. For example, multi-hydrogen bonds between base pairs construct the DNA double helix. When the adenine (A) base, for example, is UV irradiated, A is converted to its tautomer (A ), and the resultant tautomer A is misread as guanine (G) and is paired with cytosine (C) (Fig. 1) instead of thymine. Such a miscoding can become the origin of mutation (Watson and Crick, 1953 Goodman, 1995). [Pg.220]

Two polynucleotide strands form the double helix of DNA. The backbone of each polymer strand is composed of sugar-phosphate residues. Hydrogen bonding of base pairs (A-T and C-G) holds the two strands of DNA together. [Pg.1065]

Figure 27.13. Minor-Groove Interactions. DNA polymerases donate two hydrogen bonds to base pairs in the minor groove. Hydrogen-bond acceptors are present in these two positions for all Watson-Crick base pairs including the A-T base pair shown. [Pg.1116]


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See also in sourсe #XX -- [ Pg.780 , Pg.781 , Pg.785 , Pg.787 ]




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Base pairing bases

Base pairs

Bases Base pair

Bonded pairs

Bonding pair

DNA base pairing

DNA bases

DNA hydrogen bonding

DNA hydrogen bonds

Hydrogen bases

Hydrogen bonding base pairing

Hydrogen pairing

Hydrogen-bonded base pairs

Hydrogen-bonded pair

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