Hydrogen bond interactions donor group

For 23, both hydroxyl groups in the cis- and /ra t-isomer act as donors in intermolecular two-center and three-center O-H O hydrogen bonding, which may be classified as medium strong and weak. Additionally, there are C-H O hydrogen-bonding interactions in each crystal that in the ftf-isomer is intramolecular <2003JST(647)223>. 

Solvation, the interaction of a solute with the solvent, makes an important negative contribution to the entropy of a solution. Solvation can take the form of hydrogen bonding to donor or acceptor groups on the solute, or of a looser clustering of solvent molecules oriented around the solute (fig. 2.3). In general, the entropy of solvation by water be-... 

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