Hydrogels cross-linking agents

Degeneration, 25 205 Degradable-cross-linking-agent hydrogels, 13 740-741... 

Some problems that can occur with the fabrication of hydrogels are difficulty in adherence to the surface, mechanical stability problems when implanted, some precursors (monomer, solvent, cross-linking agent, UV light) can harm the enzyme or other sensor components, and some hydrogels can limit the diffusion of the desired analyte to the sensor.31... 

Fig. 2 Chemical structures of some cross-linking agents used in the synthesis of hydrogels.

Fig. 4 Relationship between structure and properties of hydrogels. The selection of monomers and cross-linking agent determines hydrogel properties. On the other hand, a hydrogel with specific properties must be synthesized using specific monomers and cross-linking agent.

Because hydrotropic polymers can be diluted when introduced into aqueous solution, cross-linked hydrotropic polymers, i.e., hydrotropic hydrogels, were prepared. Hydrotropic hydrogels are prepared by polymerization of hydrotropic monomers in the presence of cross-linking agents. Despite the cross-linking of linear hydrotropic polymer chains, the hydrogels maintained the hydrotropic property. The hydrotropic hydrogel... 

Fig. 1 Representative methods of hydrogel formation. (A) Chemically cross-linked hydrogels are prepared from monomers, oligomers, or polymers in the presence of cross-linking agents. The chemical cross-linking proceeds via radical polymerization or polycondensation reaction. (B) Physically cross-linked hydrogels can be formed by ionic interactions, hydrophobic interaction, or hydrogen bonding.

A copolymer of this monomer with N,N melhylenebis (acrylamide) imbibed 100 times its weight of water. This swelling was not affected by sodium chloride in the water. Most super-slurpers swell less in the presence of dissolved salts. Thus, the new copolymer may be of use in collecting urine in diapers. Another polymeric hydrogel was made by polymerization of sucrose-l -acrylate using sucrose-6,1 -diacrylate (prepared by enzymatic transesterification of sucrose and vinyl acrylate) as the cross-linking agent.155... 

The cross-linked PNIPAAm hydrogels were prepared according to (Arndt et al. 2000) by free radical polymerization of NIPAAm in water with V, V -methylene-bisacryla-mide (MBAAm MBAAm content 4 mol%) as the cross-linking agent. A solution of... 

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