Hydrocortisone butyrate cream and ointment

The cream, ointment, and topical solution contain the topical corticosteroid hydrocortisone butyrate, a nonflu-orinated hydrocortisone ester. It has the chemical name pregn-4-ene-3,20-dione, 11,21 -dihydroxy-17- [(1 -oxobu-tyl)oxy-,(ll(beta))- the molecular formula is C25H3606 and the molecular weight is 432.54. Each gram of cream contains 1 mg hydrocortisone butyrate in a hydrophilic [Pg.169]

Handbook of Pharmaceutical Manufacturing Formulations Semisolid Products [Pg.170]