Hydroalumination catalytic asymmetric

In this chapter, recent advances in asymmetric hydrosilylations promoted by chiral transition-metal catalysts will be reviewed, which attained spectacular increase in enantioselectivity in the 1990s [1], After our previous review in the original Catalytic Asymmetric Synthesis, which covered literature through the end of 1992 [2], various chiral Pn, Nn, and P-N type ligands have been developed extensively with great successes. In addition to common rhodium and palladium catalysts, other new chiral transition-metal catalysts, including Ti and Ru complexes, have emerged. This chapter also discusses catalytic hydrometallation reactions other than hydrosily-lation such as hydroboration and hydroalumination. 

In the realm of olefin hydrometalation, the hydroboration reaction has largely dominated the scene. This is in no small part due to the early work by Brown in the development of this reaction class to a level of sophistication that permitted its evolution as a reliable and common tool in the service of complex molecule synthesis. There are, however, closely related catalytic asymmetric hydrometalation reactions of olefins that provide alternatives to enantioselective hydroboration namely, the hydroalumination [14] and hydrosilylation reactions [16]. 

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