HYBRIDIZATION WITH NUCLEIC ACID PROBES purification

The latter class of bioorganic materials has gained momentum during the recent years, mainly because many functions have been implemented and potential applications realized [4]. The combination of nucleic acids with conjugated polymers [5] or electroactive macromolecules [6] has resulted in highly sensitive and selective probes, whilst equally important are polynucleic acids that are coimected covalently to thermoresponsive polymers such hybrids have been used successfully for the purification of plasmid DNA [7] and DNA-binding proteins [8]. 

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