Hyaluronic acid, /3-eliminative degradation

These /8-elimination reactions, which were proved for n-glucopyran-uronate derivatives, belong to the class of axialr-equatorial reactions (type B). This type of enolacetal-forming, /8-elimination reaction is found in the enzyme-catalyzed degradation of hyaluronic acid and chondroitin 4- and 6-sulfates. 

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