Hyaluronan enzymatic polymerization

Kobayashi S, Morii H, Itoh R, Kimura S, Ohmae M. Enzymatic polymerization to artificial hyaluronan a novel method to synthesize a glycosaminoglycan using a transition state analogue monomer. J. Am. Chem. Soc. 2001 123 11825-11826. 

Figure 9.15 Enzymatic polymerization of various monomers (series 1) to synthetic hyaluronan and its derivatives (series 2). (Reproduced with permission from [231]. Copyright (2005) American Chemical Society).

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