Humulones anti-hyperglycemic effects

Fig. (14 b). Dose-dependent anti-hyperglycemic effects of humulones (a mixture of 65% humulone, 24% cohumulone, 9% adhumulone, and 2% other a-acids) and isohumulones 6 hr after intraperitoneal injection in streptozotocin-diabetic mice. Isohumulones were prepared from humulones in 0.1% DMSO solution by heating at 60°C for 1 hr. The percentage fall of blood glucose level was evaluated from the expression of (b-a)/(b-85) x 100, where b and a are blood glucose levels before and after injection of the compounds, respectively, and 85 mg/dL is the mean blood glucose level in the fasted state of normal mice. The values represent means S.E.M. (n = 3-7). 

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