Human hypoxia

Figure 5.1. The interplay between time and adaptational options occurs in human as well as in animal evolution of physiological systems. The acute and acclimation effects on human hypoxia response physiology can be readily evaluated. However, adaptations requiring generations of time of course cannot be studied by direct manipulations in humans. All workers in this area therefore rely upon comparing human lineages adapted to hypobaric hypoxia in different regions of the world and for different time periods. Two such groups that have extensively studied in this manner are Quechuas and Aymaras from the Andes, and Sherpas and Tibetans from the Himalayas. See chapter 1 for further discussion of time and adaptation options.

CAN MOLECULAR EVOLUTION MODELS EXPLAIN ADAPTABLE TRAITS IN HUMAN HYPOXIA TOLERANCE ... 

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