Human genome information

D. W. Ross The human genome information content and structure. Hospital Practice, June 15, 49 (1999). 

The immediate medical application of human genome information is in identification and annotation of genes associated with disease, the pursuit of new diagnostics, and treatments for these diseases. About 5000 human diseases are known to have a genetic component and 1000 disease-associated markers or... 

So efficient is the automated dideoxy method that sequences up to 1100 nucleotides in length, with a throughput of up to 19,000 bases per hour, can be sequenced with 98% accuracy. After a decade of work, preliminary sequence information for the entire human genome of 2.9 billion base pairs was announced early in 2001- Remarkably, our genome appears to contain only about 30,000 genes, less than one-third the previously predicted number and only twice the number found in the common roundworm. 

Information flowing from the Human Genome Project is having major influences in fields such as proteomics, bioinformatics, biotechnology, and pharmacogenomics as well as all areas of biology and medicine. 

Human Genome Project Information http //www.ornl.gov/hgmis/ (From the Human Genome Program of the United States Department of Energy.)... 

Extensive information about the Human Genome Project.) National Institutes of Health (NIH) http //www.nih.gov/... 

In 1990, work was started to characterize the human genome which had been shown to consist of about 3 billion base pairs. The final result was announced in the year 2000. All of the chromosomes have been characterized. The human genome has been shown to contain some 30,000 genes (which are sections of the chromosome which code for specific proteins). Each cell produces the t T)e of proteins needed for it to function. The function of mRNA is to transfer information from the DNA. so as is to fix the limits of the protein needed. The vast majority of the proteins found in living organisms are composed of only 20 different kinds of amino acids, repeated many times and strung together in a particular order. Each type of protein has its own unique sequence of amino acids. This sequence, known as its primary structure, actually... 

DNA analysis has become an invaluable tool having very many practical applications that aim to open new frontiers in science. The sequencing of the human genome will provide information that could be applied to the study of genetic disorders as well as complications affecting the behaviour of humans at molecular level. 

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