Transport hormone

Fujiwara, K., et al. Identification of thyroid hormone transporters in humans different molecules are involved in a tissue-specific manner. Endocrinology 2001, 342, 2005-2012. 

Transport of thyroid hormones Transport of vitamin A Osmotic regulation of plasma Non-specific carrier... 

Alteration of thyroid hormone transport and serum total T 3 and T4 levels, but usually no modification of FT 4 or TSH ... 

Polybrominated Diphenyl Ethers. Results of in vitro estrogen receptor and thyroid hormone transport protein binding assays and in vivo studies of thyroid hormone homeostasis indicate that PBDEs have the potential to disrupt normal endocrine function. 

Proteins are the most abundant of cellular components. They include enzymes, antibodies, hormones, transport molecules, and even components for the cytoskeleton of the cell itself. Proteins are also informational macromolecules, the ultimate heirs of the genetic information encoded in the sequence of nucleotide bases within the chromosomes. Structurally and functionally, they are the most diverse and dynamic of molecules and play key roles in nearly every biological process. Proteins are complex macromolecules with exquisite specificity each is a specialized player in the orchestrated activity of the cell. Together they tear down... 

Hypothyroidism induced by peripheral insensitivity to thyroid hormones, inadequate hormone transport, other causes... 

Fujiwara K, Adachi H, Nishio T, Unno M, Tokui T, Okabe M, Onogawa T, Suzuki T, Asano N, Tanemoto M, Seki M, Shiiba K, Suzuki M, Rondo Y, Nunoki K, Shimose-gawa T, Iinuma K, Ito S, Matsuno S, Abe T (2001) Identification of thyroid hormone transporters in humans different molecules are involved in a tissue-specific manner. Endocrinology 142, 2005—2012. 

Reduced synthesis of proteins in the liver can also affect the end omnium. Thyroxine-binding globulin (TBG), the major thyroid hormone transport protein, has been found to be transiently but marisedly decreased during I-ASP therapy [129,130]. In extended observations Ferster et al. [131] demonstrated a decrease of total T4, FT4, total T3, and TBG during induction therapy. The changes in T4... 

Mammalian cell culture is the most important source of therapeutic proteins and monoclonal antibodies. Just as mammalian cells are more complicated than most other microorganisms, the media required for their growth is also more complex. The extracellular medium must provide the same nutrients and growth factors that mammalian cells are exposed to in vivo in order for them to survive, proliferate, and differentiate. Serum contains many important components that support the growth of mammalian cells including growth factors, hormones, transport and binding proteins, attachment factors, protease inhibitors, and... 

Hormone transport. Steroid hormones bind to carrier proteins and are transported in the blood stream to their required sites. At these sites, the hormones transfer to storage sites while they await release for use. When these carrier proteins are interfered with, the hormones are not delivered to the required sites. 

Stockigt JR. Chapter 18 Serum thyrotropin and thyroid hormone measurements and assessment of thyroid hormone transport. In Braverman LE, Utiger RD, eds. Werner and Ingbar s the thyroid. 7th ed. Philadelphia Lippincott-Raven, 1996 377-96. 

Friesema, E.C., Docter, R., Moerings, E.P., Stieger, B., Hagenbuch, B., Meier, P.J., Krenning, E.P., Hennemann, G. and Visser, T.J. (1999) Identification of thyroid hormone transporters. Biochemical and Biophysical Research Communications,... 

Zhou, Y., Samson, M., Osty, J., Francon, J., and Blondeau, J. P, Evidence for a close link between the thyroid hormone transport system and the aromatic amino acid transport system T in erythrocytes, ]. Biol. Chem., 265(28], 17000, 1990. 

B17. Braverman, L. E., Foster, A. E., and Ingbar, S. H., Thyroid hormone transport in the serum of patients with thyrotoxic Graves disease before and after treatment. J. Clin. Invest. 47, 1349-1357 (1968). 

R9. Robbins, J., and Rail, J. E., II. Hormone transportation in circulation Interactions of thyroid hormones and proteins in biological fluids. Recent Progr. Hormone Res. 13, 166-208 (1957). 

Friesema, E. C. et al. 1999. Identification of thyroid hormone transporters. Biochemical and Biophysical Research Communications 254 497-501. 

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