Hormone cardiotonic

Although the limitations in the cases that provide good yields may appear to be very restrictive, this last example is suggestive of the potential applications of this procedure. Rather obvious possibilities that follow from this case include derivatives of the equilinin steroidal hormone system,11 and of the steroidal cardiotonic agents, e.g., the cardenolides, digitoxigenin, bufadienolides, etc.12... 

In the UK digoxin is among the 20 most prescribed drugs. A more recent approach to the development of cardiotonic agents is shown by dobutamine (Lilly, 1977) which is a mimic of dopamine, a natural hormone with heart-stimulating properties. 

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