Homologous recombination models

HMG CoA-Reductase HMG-CoA-Reductase Inhibitors Homologous Desensitization Homologous Proteins Homologous Recombination Homology Modeling Hormonal Contraceptives Hormone Replacement Therapy (HRT)... 

A likely pathway for homologous recombination during meiosis is outlined in Figure 25-31a. The model has four key features. First, homologous chromosomes are aligned. Second, a double-strand break in a DNA mole-... 

Figure 22.19. Mechanistic models for the formation of chromosomal aberrations. Regions of sequence homology (e.g., repeats and pseudogenes) are shown as black boxes with the arrow indicating orientation. HR, homologous recombination NHEJ, nonhomologous end joining SSA, single-strand annealing.

Figure 23.14. A general model for double-strand break repair using homologous recombination. The text in parentheses to the right indicates proteins that participate in each step in E. coli. The light blue lines indicate newly synthesized DNA. (Reproduced with permission from Kowalczykowski, S.C. Initiation of genetic recombination and recombination-dependent replication. Trends Biochem. Sci. 25 156-165, 2000.) See color insert.

---