Homologous blood transfusions

Table 20.3 Potential adverse effects of homologous blood transfusions ...

Murphy, P. Heal, J.M. Blumberg, N. Infection or suspected infection after hip replacement surgery with autologous or homologous blood transfusions. Transfusion 1991, 31, 312-317. 

Finally, several studies have shown depressed immune function post-transfusion of RBCs i.e., patients with different tumors had a shorter disease-free survival and a higher incidence of recurrent or metastatic cancers or a higher rate of postoperative infections after homologous blood transfusions. ° ... 

Durandy, Y.D. 2009. Pediatric cardiac surgery Effect of a miniaturized bypass circuit in reducing homologous blood transfusion. / Thorac Cardiovasc Surg 138 1454 author reply 1454-55. 

Cellular cytokines (interferons, G-CSF) and immune response modifiers originally produced from human cells, most often leukocytes, have now been replaced with recombinant products with well-defined structure/function. Futuristic advances in experimental hematology portend development of human blood cells produced from the hemopoetic stem cells. Yet for the foreseeable future, homologous blood donated by healthy, altruistic voluntary blood donors remains the principal source of safe and adequate supply of blood and blood products for transfusion therapy. 

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