Homochiral MOCPs

Scheme 9.2 Synthesis of homochiral MOCP 1 and its catalytic application in the enantioselective transesterification of racemic l-phenyl-2-propanol.

General Considerations on the Design and Construction of Homochiral MOCP Catalysts... 

The use of a ditopic or polytopic chiral hgand (building blocks) bearing two or more ligahng units to hnk adjacent, catalyhcahy achve metal centers, where the achve sites are incorporated into the main backbone of the resulhng homochiral MOCP (Scheme 9.3a). 

The use of chiral polyfunchonal hgands as linkers and metal ions or clusters as nodes to conshuct homochiral MOCPs however, the achve sites do not take part... 

In ideal scenarios, porous homochiral MOCPs with accessible and/or uniform catalytic sites can be obtained and used to catalyze asymmetric organic transformations in heterogeneous fashion. 

When the desired chiral polytopic ligands are at hand, the synthetic protocols for accessing homochiral MOCP catalysts can be quite simple. A combination of the ligand with an appropriate metal precursor in a compatible solvent under appropriate conditions, can result in the spontaneous formation of insoluble polymers by self assembly. This polymerization process involves the successive... 

Type I Homochiral MOCP Catalysts in Heterogeneous Asymmetric Reactions 333... 

High contents of asymmetric units in a homochiral MOCP do not always guarantee excellent enantioselectivity in a reaction. Lin and coworkers have reported the... 

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