Hit and lead profiling

While we do not use directly the above approach in this book, many chapters remind you that hit and lead profiling is close to detective work. It is equally exciting it carries a large volume of unknown elements which can only be dealt vdth using refined tools and protocols.. But what is most rewarding in this job is that correction, or to be precise, optimization is built into it. 

Hit and Lead Profiling. Edited by Bernard Faller and Laszlo Urban Copyright 2009 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim ISBN 978-3-527-32331-9... 

Genetic Toxicity In Vitro Approaches for Hit and Lead Profiling... 

Dr. Laszlo Urban is currently Executive Director and Global Head of Preclinical Safety Profiling at Novartis Institutes for Biomedical Research. Dr. Urban has been actively involved in organizations such as the European Neuropeptide Club, the Society for Biomolecular Sciences, and the International Association for the Study of Pain. His most recently published work is Hit and Lead Profiling Identification and Optimization of Drug-Like Molecules (2009). 

---