Historical perspectives early chemical developments

The modem world of chemical synthesis is unthinkable without NMR spectroscopy. Especially in organic synthesis, the information content of a combination of various NMR techniques is tremendeous and unmatched by any other spectroscopic method. Thus, since ionic liquids ( ILs for short) are predominantly used as solvents these days, the application of magnetic resonance spectroscopy to ionic solvents has become very important. None the less, the unique properties of this modem solvent class has put quite some challenge to researchers trying to apply NMR for ILs. In this review, I will describe the development of NMR in modem (i.e. air- and moisture-stable, predominantly imidazolium-based) ILs of the last 8 years historically from an experimental perspective. If you are looking for a more substrate-specific point of view or are interested in the early developments with chloroaluminate ILs, you are kindly asked to refer to the recent literature [1],... 

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