Historical perspective structure-activity relationships

Kallr, A. Structure activity relationships of phencyclidine derivatives. In Domino, E.F., ed., PCP (Phencyclidine) Historical and Current Perspectives. Ann Arbor, MI. NPP Books. 1981. p. 31-46. [Pg.76]

T.W. Schultz et al., Quantitative structure-activity relationships (QSARS) in toxicology A historical perspective. THEOCHEM 622, 1-22 (2003)... [Pg.213]

In this chapter we provide a historical perspective of the development of the field of computational toxicology. Beginning from the similarity-based grouping of elements into the periodic table, the chapter presents a chronology of developments from the simple observations of qualitative relations between structure and toxicity through LFER (linear free energy related) and QSAR (quantitative structure activity relationship) models, to the current... [Pg.184]

Hansch, C., Selassie, C. Quantitative structure—activity relationship — a historical perspective and the future. In Comprehensive Medicinal Chemistry 2 Ed., vol. 4, Computer-Assisted Drug Design, (Taylor, J. B., Triggle, D. J., Eds), Elsevier Oxford, 2007, pp. 43-63. [Pg.510]

Hansch, C. Selassie, C. Quantitative Structure-Activity Relationship-a Historical perspective and the Future, Elsevier Oxford, 2007. [Pg.207]