Historical development of drug regulation

Venezuela developed its dmg regulation system relatively early. Its first dmg-related law was issued in 1883 as the Ordinance of the Council of Physicians on Secret Medicines and Patents. Dmg laws have been revised regularly a significant number of dmg laws were adopted over the course of the 20 century. The law which established the dmg registration system— the Law on the Exercise of the Pharmacy— was passed 

Under the terms of the Act, the TGA was created. It combined the old Therapeutics Division within the Department of Health with the National Biological Standards Laboratory. 

Regulation of medicines in Zimbabwe started in 1969, with the promulgation of the Dmgs and Allied Substances Control Act, Chapter 320. This Act created the Dmgs Control Council (a body corporate), which started operations in 1971. The 1997 amendment transformed the Dmgs and Allied Substances Control Act into the Medicines and Allied Substances Control Act (MASCA), Chapter 15 03, which established the Medicines Control Agency of Zimbabwe (MCAZ), with increased authority. 

Some observations can be made on the basis of the country data relating to the historical development of dmg regulation. 

which has the longest dmg regulation experience in this group, issued its royal act Real Tribunal Protomedicato in 1709 to control the conduct of professionals, rather than pharmaceutical products themselves. Before the industrialization of pharmaceutical production, dmgs were made up and dispensed to individual patients in pharmacies. Accordingly, attempts to protect patients were aimed first at the activities of the professionals who practised pharmacy rather than at the products themselves, which at that time were being manufactured on a small scale only. 

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