High-throughput purification HTP

In high-throughput purification (HTP) the 96-well microtiterplate is the common housing for sample handling. Mainly deep-well or the shallow-well plates with a sample capacity of about 1 mL or 50pL per well are used.Thus... 

For high-throughput purification pipelines, quality assessment (QA) procedures are required which can be carried out in parallel in relatively high throughput. The QA steps routinely carried out in the OPPF are summarized in Table 2.3. Other methods that have been used in HTP projects include one and two-dimensional NMR screening and differential scanning calorimetry. 

Figures 1 illustrates the separation efficiency of the high throughput purification fractionation method on an organic extract from the roots of Pulsatilla chinensis. Every other HTP fraction was spotted on a silica gel...

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