High speed ball milling technique

Scheme 1.24 The Heck-Mizoroki reaction using the high-speed ball milling (HSBM) technique as described by Su s group [68].

In a recent report using the environmentally friendly high speed ball milling (HSBM) technique, Mack and Shumba described a dramatic increase in reaction rate of the MBH reaction betvv een />-nitrobenzaldehyde 30 and methylacrylate 4 in the presence of DABCO. ° In the event, all reagents were placed in a stainless steel vial and milled with a stainless steel ball-bearing for 30 minutes to afford the MBH adduct 58 in high yield. Previous reports using solvent-free conditions required three to four days and delivered the product in 70-87% yield. 

A certain proportion of fluoroelastomers is used in latex form. The compounding techniques used are similar to those used for standard latexes i.e., solid ingredients are first dispersed in water with the use of surface active agents and liquid ingredients are prepared as emulsions prior to their addition to the latex. The dispersions of solids are prepared in ball mills or high-speed mills (e.g., Kady). 

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