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High-energy phosphate depletion

Reimer KA, Jennings RB, Hill ML (1981) Total ischemia in dog hearts, in vitro. 2. High energy phosphate depletion and associated defects in energy metabolism, cell voliune regulation, and sarcolemmal integrity. Circ Res 49 901-911... [Pg.390]

L. F. Wexler, B. H. Lorell, S. Momomura, E. O. Weinberg, J. S. Ingwall, C. S. Apstein, Enhanced sensitivity to hypoxia-induced diastolic dysfunction in pressure-overload left ventricular hypertrophy in the rat role of high-energy phosphate depletion, Circ Res 62, 766-75 (1988). [Pg.187]

Creatine phosphate prevents the rapid depletion of ATP by providing a readily available high-energy phosphate that can be used to regenerate ATP from ADP. [Pg.573]

Adenosine triphosphate (ATP) is the primary energy source for ceU-free synthesis reactions. Rapid depletion of ATP leads to the cessation of translation in under an hour in batch mode. ATP regeneration systems are used to extend the life of translation reactions by maintaining a stable ATP concentration. ATP is regenerated by the enzyme-catalyzed transfer of high-energy phosphate bonds from a secondary energy... [Pg.1074]

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