High-density lipoproteins drugs affecting

A 47-year-old male is seen in the medicine clinic with recently diagnosed mixed hyperlipidemia. An anti hyp er lip idem ic is administered that favorably affects levels of VLDL, low-density lipoprotein (LDL), and high-density lipoprotein (IIDL) and inhibits cholesterol synthesis. This drug is ... 

FIG. 1 Schematic diagram of cholesterol transport in the tissues, with sites of action of the main drug affecting lipoprotein metabolism (C = cholesterol CE = cholesteryl ester TG = triglycerides MV A = mevalonate HMG-CoA reductase = 3-hydroxy-3-methyl-glutaryl-CoA reductase YLDL = very low density lipoproteins LDL = low density lipoproteins HDL = high density lipoproteins). (Reprinted from Rang et al (1999), with permission from Elsevier Science.)... 

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