Hexahydric alcohol

Mannitol, CH,0H(CH0Hi4CH40H, is a hexahydric alcohol obtained by the reduction of mannose. Since ring formation does not occur in mannitol, the hexacetyl derivative can exist in only one form, and therefore either zinc chloride or sodium acetate can be used as a catalyst for the acetylation. 

Chemical DesignationsD-Glucitol Hexahydric alcohol 1,2,3,4,5,6-Hexanehexol Sorbit Sorbo Sorbol Chemical Formula CH20H(CH0H)4CHj0H. 

Sorbitan [C6H80(0H)4] products have a particularly low toxicity level, being derived from the hexahydric alcohol sorbitol [CH2OH (CHOH)4 CH2OH], which is, in turn, produced by the reduction of glucose sugar. 

The ijo-Propylidene Derivatives of Hexahydric Alcohols. Part II. i.vo-Propylidene Derivatives of Sorbitol (D-Glucito )," E. J. Bourne, G. P. McSweeney, M. Stacey, and L. F. Wiggins, /. Chem. Soc.,... 

The anhydrides of hexahydric alcohols have already achieved marked usefulness in chemical industry and many of their derivatives show definite promise of value in industry and in medicine. 

What are the products of oxidation and reduction of the monosaccharides Mucic add, of which the preparation from d-galactose has been described, is optically inactive and incapable of resolution, just like duldtol, the corresponding hexahydric alcohol. As the formula shows, the four asymmetric carbon atoms of galactose form two pairs (2, 5 and 3, 4) having the same substituents but opposite arrangement in space, and when the carbon atoms 1 and 6 become alike, inactive forms are produced by intramolecular compensation, as in mesotartaric acid. 

Sorbitol is a hexahydric alcohol that is isomeric with mannitol, and which has been described as a humectant, plasticizer, sweetening agent, and tablet and capsule diluent. It is used extensively in the pharmaceutical, cosmetics, and food industries, since it has a sweet taste and approximately 50-60% the sweetness of sucrose. 

Brand Name(s) Osmitrol, Resectisol Chemical Class Hexahydric alcohol... 

It is a cyclic hexahydric alcohol, which is optically inactive. Exists also in two optical modifications ... 

E.von Herz et al.GerP 708238(1941) CA 37,2938(1943) (A priming compn, sensitive to flame, impact or friction, is made of a mixt of a nitrate, a tetra-, penta- or hexahydric alcohol, Tetracene ... 

In this review of the metabolism of the sugar alcohols emphasis will be centered mainly on the isomeric hexitols. Substances such as methyl alcohol and ethylene glycol are studied under categories other than the sugar alcohols. Furthermore, in common parlance, the term, sugar alcohol, as a rule, refers to the hexahydric alcohols and their availability as food in the human diet warrants special study of their metabolic patterns. 

D-Sorbitol is perhaps the most abundantly used of the hexahydric alcohols. The cost of sorbitol obtained from natural sources limited considerably its early metabolic studies in this country. However, European investigators have carried on rather extensive clinical studies with sorbitol during the last fifteen years. European methods of producing sorbitol in commercial quantities seem to antedate ours by several years. Sorbitol was introduced into therapeutics in Europe under the name of Sionin by Thannhauser and Meyer in 1929. ... 

The English workers, Payne and coworkers,contrary to the findings of the continental investigators, reported that sorbitol was not directly metabolized, and they recommended it as an inert condiment in the diabetic diet. One of the first accounts of the metabolism of sorbitol in America was written by Silver and Reiner. These workers found that the ingestion of the hexahydric alcohol produced hj perglycemia in a diabetic patient. 

Mannitol is D-mannitol. It is a hexahydric alcohol related to mannose and is isomeric with sorbitol. 

Sorbitol is a hexahydric alcohol obtained from the hydrogenation of fructose-free glucose, usually obtained from com [8]. The reaction is ... 

Span and Tween . Nonionic surface active agents, complex esters, and ester-ethers, their chemical starting point being hexahydric alcohols, alkylene oxides, and fatty acids. 

D-Mannitol, mannite or manna sugar is the name applied to this hexahydric alcohol widely distributed throughout the vegetable kingdom. It comprises as much as 75% of the medicinal saccharin exudation known as manna, Fraxinus ornus. The compound was isolated first by Proust in 1806. The early metabolic studies on mannitol were carried out with the naturally occurring alcohol in manna, which is n-mannitol. 

---