Heterogeneous nuclear ribonucleoprotein

Ferro A, Olivera B (1982) Poly(ADP-ribosylation) in vitro. J Biol Chem 257 7808-7813 Gagne JP, Hunter JM, Labrecque B, Chabot B, Poirier GG (2003) A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins. Biochem J 371 331-340... 

Bertrand, E.L. and Rossi, J.J. (1994) Facilitation of hammerhead ribozyme catalysis by the nucleocapsid protein of HIV-1 and the heterogeneous nuclear ribonucleoprotein Al. EMBO J., 13,2904-2912. 

Figure 13.1 Schematic representation of mRNA biogenesis. The nascent mRNA associates with a subset of RNA-binding proteins, termed heterogeneous nuclear ribonucleoproteins (hnRNPs) and splicing. Through specific protein-protein, hnRNPs direct the assembly of processing factors to the newly synthesized mRNA. hnRNPs remain associated with the pre-mRNA until processing is complete and some stay with the mature mRNA during nuclear export.

Weighardt, F., Biamonti, F. and Riva, S. (1996) The roles of heterogeneous nuclear ribonucleoproteins (hnRNP) in RNA metabolism. BioEssay, 18, 747-756. 

Sueoka E, Sueoka N, Goto Y, Matsuyama S, Nishimura H, Sato M, et al. Heterogeneous nuclear ribonucleoprotein B1 as early cancer biomarker for occult cancer of human lungs and bronchial dysplasia. Cancer Res 2001 61(5) 1896-1902. 

Iwanaga K, Sueoka N, Sato A, Hayashi S, Sueoka E. Heterogeneous nuclear ribonucleoprotein B1 protein impairs DNA repair mediated through the inhibition of DNA-depen-dent protein kinase activity. Biochem Biophys Res Commun 2005 333(3) 888-895. 

Expression, phosphorylation, and mRNA-binding of heterogeneous nuclear ribonucleoprotein K in Xenopnis oocytes, eggs, and early embryos. Dev Growth Differ 50(l) 23-40. 

Matunis, M. J., Michael, W. M., and Dreyfuss, G. (1992) Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein. Mol. Cell. Biol. 12, 164-171. 

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