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Heterocycles in drug discovery

Applications of MCR-Derived Heterocycles in Drug Discovery Table 6 Antibacterial activities of select pyrazolo-pyrido-pyrimidine-diones... [Pg.249]

Sperry JB, Wright DL (2005) Furans, thiophenes and related heterocycles in drug discovery. Curr Opin Drug Discov Dev 8 723-740... [Pg.19]

In this section, only a small portion of marketed drugs are shown to illustrate the importance of hetereocyclic chemistry in drug discovery. Many drugs containing saturated heterocycles, heterocycles with more than two heteroatoms, and non-heterocycles. In the ensuing chapters, the most popular types of heterocycles in drug discovery are reviewed for their physical and chemical properties, their constructions in the context of medicinal chemistry, and their potential liabilities as drugs when applicable. [Pg.16]


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See also in sourсe #XX -- [ Pg.8 , Pg.9 , Pg.10 , Pg.11 , Pg.12 , Pg.13 , Pg.14 , Pg.15 ]




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