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Heterocycles homogeneous

Keywords Coordination complexes, Heterocycles, Homogeneous catalysts, Phosphinines, Phosphorus compounds. [Pg.74]

Complexes with chiral heterocycles possessing P-containing substituents as P-mono- andP,N-bidentate ligands and their use in homogeneous asymmetric catalysis 98KK883. [Pg.219]

Chiral P-heterocycles as P-mono- and P,N-bidentate ligands in the synthesis of coordination compounds and homogeneous asymmetric catalysis 98KK883. [Pg.271]

Abstract The use of A-heterocyclic carbene (NHC) complexes as homogeneous catalysts in addition reactions across carbon-carbon double and triple bonds and carbon-heteroatom double bonds is described. The discussion is focused on the description of the catalytic systems, their current mechanistic understanding and occasionally the relevant organometallic chemistry. The reaction types covered include hydrogenation, transfer hydrogenation, hydrosilylation, hydroboration and diboration, hydroamination, hydrothiolation, hydration, hydroarylation, allylic substitution, addition, chloroesterification and chloroacylation. [Pg.23]

MW heated reactions in homogeneous media, using either neat reagents or in the presence of solvents, may also be performed at atmospheric pressure. This approach has been used particularly by Bose et al. [17]. (MORE Chemistry), who reported, for example, the rapid synthesis of heterocycles [18] in open vessels. Another approach, which avoids hazards due to the flammability of solvents, is to perform the reactions under reflux in a MW oven, which is modified to allow the reaction vessel to be attached to a reflux condenser outside the MW oven [7, 19]. It should be pointed out, however, that most of the available evidence shows that rate enhancements of MW heated reactions in homogeneous media at atmospheric pressure are small or nonexistent [19], This will be discussed in more detail later in this review (see also Chapt. 5 of this book). [Pg.116]

The purpose of this section is to highlight the applications of microwave irradiation to multistep synthesis of polyheterocyclic systems with potent pharmaceutical value. When conventional thermal procedures (metal or oil bath) fail, and irrespective of the conditions needed in the homogeneous phase, microwave irradiation can be used as an alternative to classical methods enabling development of easy and rapid access to new heterocycles. [Pg.258]

Diaz-Ortiz described the microwave-induced 1,3-dipolar cycloadditions of the me-sitonitrile oxide 10 with aliphatic and aromatic nitriles in solvent-free conditions [99]. The procedure allowed the corresponding heterocyclic adducts, the 1,2,4-oxadia-zoles 187, to be obtained in a domestic oven. The reaction times were shorter and the yields better than those seen with the classical homogeneous reactions (Scheme 9.57). [Pg.328]

The catalytic effect of tetra-n-butylammonium fluoride in the homogeneous reduction of heterocyclic A-oxides and nitroarenes by hexamethyldisilane in tetra-hydrofuran can occur with EXPLOSIVE violence, but can be controlled by the slow addition of the disilane to the A-oxide (or nitroarene) and tetra-n-butylammonium fluoride to yield the parent heterocycle (>70%) (or azobenzene 84%). In a similar manner, azoxybenzene is converted into azobenzene (95%), and 4-nitropyridine-l-oxide, is reduced to azoxypyridine-l,l -dioxide (78%), with minor amounts of azopyridine-1, l -dioxide and azopyridine-1-oxide [5,6]. [Pg.507]

This article discusses the anodic synthesis of heterocyclic compounds that have appeared during the last decade. The mechanistic aspects involving intramolecular, intermolecular cyclizations and the homogeneous vs heterogeneous anodic oxidations were considered. This review deals with the recent advances in anodic oxidations in which heterocyclic compounds were synthesized through carbon-heteroatom and heteroatom-heteroatom bond formation. [Pg.88]

Anodic oxidation of formazane 18 [17], 1-arylmethylenesemicarbazide 19 [55], p-nitrobenzaldehyde phenylhydrazone 20 [56], and 2-benzoylpyridine phenylhydrazone 21 [57] afforded the corresponding heterocycles in a very good yield (Scheme 14). The homogeneous oxidation of compounds 18-20 was carried out by indirect electrolysis by the mediators generated in situ [58]. [Pg.104]

In laboratory-scale homogeneous catalysis applications, in the last decade further investigations have been carried out in which a less soluble organo-metallic catalyst system was utilized for metathesis reactions [46]. Under RCM-conditions, it was possible to convert substrates with functional groups that were problematic due to their potential to inactivate the rutheniiun catalyst here, the conversion in supercritical carbon dioxide avoids the protection of critical amino groups as an additional synthetic step. Consequently, it was possible to synthesize a number of carbo- and heterocyclic products with varying ring size (C4 to Cie). [Pg.8]

Iridium N-Heterocyclic Carbene Complexes and Their Application as Homogeneous Catalysts... [Pg.39]

Metal complexes of stable carbenes—or more precisely metal complexes of car-benes that are now known to be stable—have developed from laboratory curiosities to widely used compounds. The basis for this development was laid by Wanzlick s and Ofele s discoveries in the 1960s, the recent revival has certainly been driven by Arduengo s first isolation of an A-heterocyclic carbene in 1991, and the result is a permanently increasing number of synthetic routes towards precursors for stable carbenes, towards stable carbenes themselves, and their metal complexes. Simultaneously with their accessibility, the applicability of these compounds to various fields such as homogeneous catalysis, materials science, medicinal and bioinorganic chemistry has been evaluated. [Pg.58]


See other pages where Heterocycles homogeneous is mentioned: [Pg.176]    [Pg.5847]    [Pg.5846]    [Pg.138]    [Pg.176]    [Pg.5847]    [Pg.5846]    [Pg.138]    [Pg.25]    [Pg.168]    [Pg.116]    [Pg.157]    [Pg.1009]    [Pg.116]    [Pg.175]    [Pg.23]    [Pg.119]    [Pg.180]    [Pg.870]    [Pg.74]    [Pg.106]    [Pg.303]    [Pg.272]    [Pg.442]    [Pg.518]    [Pg.479]    [Pg.89]    [Pg.24]    [Pg.326]    [Pg.127]    [Pg.70]    [Pg.359]    [Pg.189]    [Pg.494]   
See also in sourсe #XX -- [ Pg.96 , Pg.102 , Pg.326 ]




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Iridium N-Heterocyclic Carbene Complexes and Their Application as Homogeneous Catalysts

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