Heteroaromatics background

Porphobilinogen and Studies of Its Biosynthesis, ft. Neier. Synthesis and Cycloaddition Reactions of Iso-Condensed Heteroaromatic Pyrroles, C. K. Sha. Azacyclopentadienyl Metal Compounds Historical Background and Recent Advances, C. Janiak and N. Kuhn. Recent Developments in the Synthesis of Marine Pyridoacridine Alkaloids, A. M. Echavar-ren. Alkaloid Synthesis Using 1-Acylpyridinium Salts as Intermediates, D. L. Comins and S. P. Joseph. Index. S S... 

A Stille-related paper reported different regioselectivities in a q clocarbo-palladation in which the multistep reaction described terminated in a Stille cross-coupling. Mechanistic studies with deuterium provided a background for a discussion of the different outcomes when alkynyl or vinyl stannanes were used. Microwave heating was found to increase the rate of the reaction with two vinyl stannanes and one heteroaromatic stannane as substrates [80]. 

Every gain in our understanding of benzene has enriched our insight into the nature of heteroaromatic compounds such as pyridine and pyrrole, prototypical of all those to be discussed in this book. It is interesting, therefore, to consider the development of structures for pyridine and pyrrole against the background of the benzene problem in the first phase of its growth and as it was affected by some of the ideas from the second phase. 

---